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Erica Gorenberg was a postdoctoral fellow in the lab from September 2020 to July 2022. She received her B.S. in Biology from Ursinus College in 2015, and her Ph.D. from Yale University’s Interdepartmental Neuroscience Program in 2020. Her Ph.D. work focused on identifying the substrates of palmitoyl protein theioesterase 1 at the synapse and its role in the neurodegenerative disease Neuronal Lipofuscinosis. Erica was also a PennPORT fellow. Erica went on to be a visiting assistant professor at Ursinus College.

Publications

Chuang, E., R.R. Cupo, J.R. Bevan, M.L. Rice, S. Mao, E.L. Gorenberg, K.L. Mack, D.M. Huryn, P. Wipf, J.L. Brodsky, and J. Shorter. (2024). Defining a small-molecule stimulator of the human Hsp70-disaggregase system with selectivity for DnaJB proteins. bioRxiv. doi: 10.1101/2024.01.11.575109. pdf file link

Gorenberg, E.L.*, S. Massaro Tieze*, B. Yücel, H.R. Zhao, V. Chou, G.S. Wirak, S. Tomita, T.T. Lam., and S.S. Chandra. (2022). Identification of substrates of palmitoyl protein thioesterase 1 highlights roles of depalmitoylation in disulfide bind formation and synaptic function. PLoS Biol. 20(3):e3001590. pdf file link (*Co-first author).

Gorenberg, E.L., and J. Shorter. (2021). Tau heckles speckles: a pathogenic mechanism in tauopathy? Neuron. 109(10):1585-1587. pdf file link

Taguchi, Y. V., E.L. Gorenberg, M. Nagy, D. Thrasher, W.A. Fenton, L. Volpicelli-Daley, A.L. Horwich, and S.S. Chandra. (2019). Hsp110 mitigates α-synuclein pathology in vivo. Proc. Natl. Acad. Sci. U.S.A. 116(48):24310-24316. pdf file link

Gorenberg, E.L., and S.S. Chandra. (2017). The function of co-chaperones in synaptic proteostasis and neurodegenerative disease. Front. Neurosci. 11:248.pdf file link

 

 


 

 

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Department of Biochemistry & Biophysics
p3
University of Pennsylvania